Consult your doctor or pharmacist about using alcohol safely. Table 2: Placebo- and Active-Controlled Trial of Glucovance in Patients with Inadequate Glycemic Control on Diet and Exercise Alone: Summary of Trial Data at 20 Weeks Placebo Glyburide. People with Type diabetes who are on insulin usually are advised to lower their insulin doses prior to starting metformin. Always follow the instructions given to you by your physician. STORAGE: Store at room temperature at 77 degrees 25 degrees away from light and moisture. The risks of lactic acidosis associated with metformin therapy, its symptoms, and conditions that predispose to its development, as noted in the WARNINGS and PRECAUTIONS sections, should be explained to patients. It is white to off-white crystalline compound uldstandard glucovance with molecular formula of C4H12ClN5 monohydrochloride and molecular weight of 165.