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However, these observations were not systematic and it is not possible to predict on the basis of this limited experience the extent to which CNSactive drug will be misused, diverted, and or abused once marketed. EMedicineHealth does not provide medical advice, diagnosis or treatment. Escitalopram escitalopram fara medic in the long-term treatment of major depressive disorder in elderly patients. Safety and effectiveness of Lexapro has been established in adolescents 12 to 17 years of age for the treatment of major depressive disorder see Clinical Studies. 27 The authors of related study note the general problem with statistical approaches: due to the rarity of suicidal events in clinical trials, it is hard to draw firm conclusions with sample smaller than two million patients.